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orphan virus : ウィキペディア英語版
orphan virus
An Orphan virus is a virus that is not associated with a disease but may possess pathogenicity.〔Li L, Delwart E. From orphan virus to pathogen: the path to the clinical lab. Current Opin Virol. 2011 Oct;1(4):282-8. doi: 10.1016/j.coviro.2011.07.006.〕
Some Orphan Viruses include Adeno-Associated Virus (Parvoviridae), Human herpesvirus 7 (Herpesviridae), Human foamy virus (Retroviridae), Human Reovirus (Reoviridae), Hepatitis G (Flaviviridae), and TT Virus (Circoviridae).
Gilbert Dalldorf, a pathologist who showed that Coxsackie viruses paralyze mice but not humans, indicated that the term ‘orphan’ was created ‘in a moment of conviviality’ by a group of virologists. 〔Mortimer, Philip P. "Orphan Viruses, Orphan Diseases: Still the Raw Material for Virus Discovery." Reviews in Medical Virology 23.6 (2013): 337-39. Web.〕
Many enteroviruses are referred to as ECHO, Enteric cytopathic human orphan viruses, because they were originally not associated with any disease. Even though many of them are associated with severe diseases, the name ECHO still continues to be used.
==See also==

*Novel virus
*Viral metagenomics
*Reoviridae

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「orphan virus」の詳細全文を読む



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